Heparanase—A single protein with multiple enzymatic and nonenzymatic functions

Heparanase (Hpa1) is expressed by tumor cells and cells of the tumor microenvironment and functions extracellularly to remodel the extracellular matrix (ECM) and regulate the bioavailability of ECM‐bound factors, augmenting, among other effects, gene transcription, autophagy, exosome formation, and...

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Detalles Bibliográficos
Autores principales: Vlodavsky, Israel, Kayal, Yasmin, Hilwi, Maram, Soboh, Soaad, Sanderson, Ralph D., Ilan, Neta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Comprehensive Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398610/
https://www.ncbi.nlm.nih.gov/pubmed/37547889
http://dx.doi.org/10.1002/pgr2.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398610/
https://www.ncbi.nlm.nih.gov/pubmed/37547889
http://dx.doi.org/10.1002/pgr2.6

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