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ENGRAILED‐1 transcription factor has a paracrine neurotrophic activity on adult spinal α‐motoneurons

Several homeoprotein transcription factors transfer between cells and regulate gene expression, protein translation, and chromatin organization in recipient cells. ENGRAILED‐1 is one such homeoprotein expressed in spinal V1 interneurons that synapse on α‐motoneurons. Neutralizing extracellular ENGRA...

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Detalles Bibliográficos
Autores principales: Lebœuf, Mélanie, Vargas‐Abonce, Stephanie E, Pezé‐Hedsieck, Eugénie, Dupont, Edmond, Jimenez‐Alonso, Lucia, Moya, Kenneth L, Prochiantz, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398658/
https://www.ncbi.nlm.nih.gov/pubmed/37534581
http://dx.doi.org/10.15252/embr.202256525