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Homotypic SCOTIN assemblies form ER‐endosome membrane contacts and regulate endosome dynamics

The ER regulates the spatiotemporal organization of endolysosomal systems by membrane contact. In addition to tethering via heterotypic interactions on both organelles, we present a novel ER‐endosome tethering mechanism mediated by homotypic interactions. The single‐pass transmembrane protein SCOTIN...

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Detalles Bibliográficos
Autores principales: Yun, Hyeri, Jung, Minkyo, Lee, Hojin, Jung, Sungjin, Kim, Taehyeon, Kim, Nari, Park, Seung‐Yeol, Kim, Won Jong, Mun, Ji Young, Yoo, Joo‐Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398665/
https://www.ncbi.nlm.nih.gov/pubmed/37377038
http://dx.doi.org/10.15252/embr.202256538