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Homotypic SCOTIN assemblies form ER‐endosome membrane contacts and regulate endosome dynamics
The ER regulates the spatiotemporal organization of endolysosomal systems by membrane contact. In addition to tethering via heterotypic interactions on both organelles, we present a novel ER‐endosome tethering mechanism mediated by homotypic interactions. The single‐pass transmembrane protein SCOTIN...
Autores principales: | Yun, Hyeri, Jung, Minkyo, Lee, Hojin, Jung, Sungjin, Kim, Taehyeon, Kim, Nari, Park, Seung‐Yeol, Kim, Won Jong, Mun, Ji Young, Yoo, Joo‐Yeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398665/ https://www.ncbi.nlm.nih.gov/pubmed/37377038 http://dx.doi.org/10.15252/embr.202256538 |
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