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Preferability of Molnupiravir, an Anti-COVID-19 Drug, toward Purine Nucleosides: A Quantum Mechanical Study

[Image: see text] Structural aspects of molnupiravir complexed with the RNA of the SARS-CoV-2 virus have been recently resolved inside the RNA-dependent RNA polymerase (RdRp), demonstrating the interactions of molnupiravir with purine nucleosides. However, the preference of molnupiravir to interact...

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Detalles Bibliográficos
Autores principales: Ibrahim, Mahmoud A. A., Shehata, Mohammed N. I., Moussa, Nayra A. M., Hemia, Randa R. A., Abd Elhafez, Heba S. M., Abd El-Rahman, Mohamed K., Sayed, Shaban R. M., Sidhom, Peter A., Dabbish, Eslam, Shoeib, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398865/
https://www.ncbi.nlm.nih.gov/pubmed/37546583
http://dx.doi.org/10.1021/acsomega.3c03215