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Loops and the activity of loop extrusion factors constrain chromatin dynamics

The chromosomes—DNA polymers and their binding proteins—are compacted into a spatially organized, yet dynamic, three-dimensional structure. Recent genome-wide chromatin conformation capture experiments reveal a hierarchical organization of the DNA structure that is imposed, at least in part, by loop...

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Detalles Bibliográficos
Autores principales: Bailey, Mary Lou P., Surovtsev, Ivan, Williams, Jessica F., Yan, Hao, Yuan, Tianyu, Li, Kevin, Duseau, Katherine, Mochrie, Simon G. J., King, Megan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398873/
https://www.ncbi.nlm.nih.gov/pubmed/37126401
http://dx.doi.org/10.1091/mbc.E23-04-0119