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Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast

The protein α-synuclein (α-syn) is one of the major factors linked to Parkinson’s disease, yet how its misfolding and deposition contribute to the pathology remains largely elusive. Recently, contact sites among organelles were implicated in the development of this disease. Here, we used the budding...

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Detalles Bibliográficos
Autores principales: Del Vecchio, Mara, Amado, Lucia, Cogan, Alexandra P., Meert, Els, Rosseels, Joelle, Franssens, Vanessa, Govers, Sander K., Winderickx, Joris, Montoro, Ayelén González
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398879/
https://www.ncbi.nlm.nih.gov/pubmed/37074954
http://dx.doi.org/10.1091/mbc.E23-01-0029