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Cell contractility drives mechanical memory of oral squamous cell carcinoma

Matrix stiffening is ubiquitous in solid tumors and can direct epithelial–mesenchymal transition (EMT) and cancer cell migration. Stiffened niche can even cause poorly invasive oral squamous cell carcinoma (OSCC) cell lines to acquire a less adherent, more migratory phenotype, but mechanisms and dur...

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Detalles Bibliográficos
Autores principales: Moon, So Youn, de Campos, Paloma Santos, Matte, Bibiana Franzen, Placone, Jesse K., Zanella, Virgı´lio G., Martins, Manoela D., Lamers, Marcelo Lazzaron, Engler, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398896/
https://www.ncbi.nlm.nih.gov/pubmed/37342880
http://dx.doi.org/10.1091/mbc.E22-07-0266