Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that differently controls migration

BACKGROUND: Colorectal cancer (CRC) can be classified into four molecular subtypes (CMS) among which CMS1 is associated with the best prognosis, while CMS4, the mesenchymal subtype, has the worst outcome. Although mitochondria are considered to be hubs of numerous signaling pathways, the study of mi...

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Detalles Bibliográficos
Autores principales: Bastin, Jean, Sroussi, Marine, Nemazanyy, Ivan, Laurent-Puig, Pierre, Mouillet-Richard, Sophie, Djouadi, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398918/
https://www.ncbi.nlm.nih.gov/pubmed/37533102
http://dx.doi.org/10.1186/s12967-023-04341-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398918/
https://www.ncbi.nlm.nih.gov/pubmed/37533102
http://dx.doi.org/10.1186/s12967-023-04341-x

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