Decreased MFN2 activates the cGAS-STING pathway in diabetic myocardial ischaemia–reperfusion by triggering the release of mitochondrial DNA

BACKGROUND: The cause of aggravation of diabetic myocardial damage is yet to be elucidated; damage to mitochondrial function has been a longstanding focus of research. During diabetic myocardial ischaemia–reperfusion (MI/R), it remains unclear whether reduced mitochondrial fusion exacerbates myocard...

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Detalles Bibliográficos
Autores principales: Xiong, Yonghong, Leng, Yan, Tian, Hao, Deng, Xinqi, Li, Wenyuan, Li, Wei, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398939/
https://www.ncbi.nlm.nih.gov/pubmed/37537600
http://dx.doi.org/10.1186/s12964-023-01216-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398939/
https://www.ncbi.nlm.nih.gov/pubmed/37537600
http://dx.doi.org/10.1186/s12964-023-01216-y

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