Cargando…

Decreased MFN2 activates the cGAS-STING pathway in diabetic myocardial ischaemia–reperfusion by triggering the release of mitochondrial DNA

BACKGROUND: The cause of aggravation of diabetic myocardial damage is yet to be elucidated; damage to mitochondrial function has been a longstanding focus of research. During diabetic myocardial ischaemia–reperfusion (MI/R), it remains unclear whether reduced mitochondrial fusion exacerbates myocard...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Yonghong, Leng, Yan, Tian, Hao, Deng, Xinqi, Li, Wenyuan, Li, Wei, Xia, Zhongyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398939/ https://www.ncbi.nlm.nih.gov/pubmed/37537600 http://dx.doi.org/10.1186/s12964-023-01216-y

Ejemplares similares

cGAS-STING triggers inflammaging-associated neurodegeneration
por: Izquierdo, José M.
Publicado: (2023)

Intercellular transmission of cGAS-STING signaling in cancer
por: Wu, Qirou, et al.
Publicado: (2023)

cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging
por: Schmitz, Carine Raquel Richter, et al.
Publicado: (2023)

Erratum to Intercellular transmission of cGAS-STING signaling in cancer
por: Wu, Qirou, et al.
Publicado: (2023)

The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
por: Hong, Christy, et al.
Publicado: (2019)

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
por: Yu, Chien-Hsiung, et al.
Publicado: (2020)

Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release
por: Liu, Huisheng, et al.
Publicado: (2023)

Molecular mechanisms of mitochondrial DNA release and activation of the cGAS-STING pathway
por: Kim, Jeonghan, et al.
Publicado: (2023)

cGAS-STING pathway in cancer biotherapy
por: Wang, Yang, et al.
Publicado: (2020)

Mitotic inactivation of the cGAS‒MITA/STING pathways
por: Zhong, Li, et al.
Publicado: (2021)

Significance of the cGAS-STING Pathway in Health and Disease
por: Zhou, Jinglin, et al.
Publicado: (2023)

Attenuation of cGAS/STING activity during mitosis
por: Uhlorn, Brittany L, et al.
Publicado: (2020)

cGAS-STING, an important pathway in cancer immunotherapy
por: Jiang, Minlin, et al.
Publicado: (2020)

Salmonella Induces the cGAS-STING-Dependent Type I Interferon Response in Murine Macrophages by Triggering mtDNA Release
por: Xu, Lei, et al.
Publicado: (2022)

Protocol for Monitoring DNA-Triggered cGAS/STING Signaling in Mammalian Cells and Mice
por: Wang, Ying, et al.
Publicado: (2020)

The cGAS–STING pathway: more than fighting against viruses and cancer
por: Bao, Terigen, et al.
Publicado: (2021)

The pleiotropic roles of cGAS–STING signaling in the tumor microenvironment
por: Li, Jun, et al.
Publicado: (2022)

cGAS-STING pathway in oncogenesis and cancer therapeutics
por: Hoong, Brandon Yi Da, et al.
Publicado: (2020)

The interactions between cGAS-STING pathway and pathogens
por: Cheng, Zhangliang, et al.
Publicado: (2020)

The Complexity of the cGAS-STING Pathway in CNS Pathologies
por: Fryer, Amelia L., et al.
Publicado: (2021)

The role of cGAS-STING signalling in liver diseases
por: Chen, Ruihan, et al.
Publicado: (2021)

cGAS/STING: novel perspectives of the classic pathway
por: Gao, Menghui, et al.
Publicado: (2020)

Advances in cGAS-STING Signaling Pathway and Diseases
por: Yang, Yuting, et al.
Publicado: (2022)

Telomere Maintenance and the cGAS-STING Pathway in Cancer
por: Ebata, Hiroshi, et al.
Publicado: (2022)

Role of cGAS–Sting Signaling in Alzheimer’s Disease
por: Govindarajulu, Manoj, et al.
Publicado: (2023)

The Activation of cGAS-STING in Acute Kidney Injury
por: Sun, Chuanchuan, et al.
Publicado: (2023)

Targeting the loss of cGAS/STING signaling in cancer
por: Sasaki, Nobunari, et al.
Publicado: (2023)

Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity
por: Wang, Chaoyu, et al.
Publicado: (2023)

The Function of cGAS-STING Pathway in Treatment of Pancreatic Cancer
por: Mohseni, Ghazal, et al.
Publicado: (2021)

cGAS-STING signaling pathway in intestinal homeostasis and diseases
por: Yang, Yuchen, et al.
Publicado: (2023)

cGAS/STING signaling in the regulation of rheumatoid synovial aggression
por: Li, Ruiru, et al.
Publicado: (2022)

cGAS–STING pathway in ischemia-reperfusion injury: a potential target to improve transplantation outcomes
por: Chen, Zijian, et al.
Publicado: (2023)

Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS
por: Webb, L. G., et al.
Publicado: (2020)

ROP16 of Toxoplasma gondii Inhibits Innate Immunity by Triggering cGAS-STING Pathway Inactivity through the Polyubiquitination of STING
por: Jin, Qi-Wang, et al.
Publicado: (2023)

HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway
por: Liao, Yajin, et al.
Publicado: (2020)

The cGAS/STING Pathway: A Novel Target for Cancer Therapy
por: Gan, Yu, et al.
Publicado: (2022)

The cGAS-STING Defense Pathway and Its Counteraction by Viruses
por: Ma, Zhe, et al.
Publicado: (2016)

cGAS-independent STING activation in response to DNA damage
por: Unterholzner, Leonie, et al.
Publicado: (2019)

Conserved strategies for pathogen evasion of cGAS–STING immunity
por: Eaglesham, James B, et al.
Publicado: (2020)

The cGAS-STING Pathway in Hematopoiesis and Its Physiopathological Significance
por: Liao, Weinian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2bi2tunbhf446d54bdfo2i4th4