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Hippocampus of the APP(NL–G–F) mouse model of Alzheimer’s disease exhibits region-specific tissue softening concomitant with elevated astrogliosis
Widespread neurodegeneration, enlargement of cerebral ventricles, and atrophy of cortical and hippocampal brain structures are classic hallmarks of Alzheimer’s disease (AD). Prominent macroscopic disturbances to the cytoarchitecture of the AD brain occur alongside changes in the mechanical propertie...
Autores principales: | Hall, Chloe M., Lasli, Soufian, Serwinski, Bianca, Djordjevic, Boris, Sheridan, Graham K., Moeendarbary, Emad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398960/ https://www.ncbi.nlm.nih.gov/pubmed/37547743 http://dx.doi.org/10.3389/fnagi.2023.1212212 |
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