Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities

Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with limited treatment options, such as the chemotherapeutic agent, temozolomide (TMZ). However, many GBM tumors develop resistance to TMZ, which is a major obstacle to effective therapy. Recently, dysregulated lipid metabolism has eme...

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Detalles Bibliográficos
Autores principales: Kao, Tzu-Jen, Lin, Chien-Liang, Yang, Wen-Bin, Li, Hao-Yi, Hsu, Tsung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398973/
https://www.ncbi.nlm.nih.gov/pubmed/37537607
http://dx.doi.org/10.1186/s12944-023-01881-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398973/
https://www.ncbi.nlm.nih.gov/pubmed/37537607
http://dx.doi.org/10.1186/s12944-023-01881-5

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