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Integration of single-cell sequencing and bulk expression data reveals chemokine signaling pathway in proliferating cells is associated with the survival outcome of osteosarcoma

BACKGROUND: Osteosarcoma, as the most common primary bone malignancy, is urgent to be well-studied on the biomarkers and therapeutic targets to improve the five-year survival rate. Transcriptomic analysis using single-cell RNA or bulk RNA sequencing has been developed to detect biomarkers in various...

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Detalles Bibliográficos
Autores principales: Yu, Lin, Hongyu, Sun, Yuxi, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399040/
https://www.ncbi.nlm.nih.gov/pubmed/37537613
http://dx.doi.org/10.1186/s12920-023-01617-5