BEDwARS: a robust Bayesian approach to bulk gene expression deconvolution with noisy reference signatures

Differential gene expression in bulk transcriptomics data can reflect change of transcript abundance within a cell type and/or change in the proportions of cell types. Expression deconvolution methods can help differentiate these scenarios. BEDwARS is a Bayesian deconvolution method designed to addr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghaffari, Saba, Bouchonville, Kelly J., Saleh, Ehsan, Schmidt, Remington E., Offer, Steven M., Sinha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399072/
https://www.ncbi.nlm.nih.gov/pubmed/37537644
http://dx.doi.org/10.1186/s13059-023-03007-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399072/
https://www.ncbi.nlm.nih.gov/pubmed/37537644
http://dx.doi.org/10.1186/s13059-023-03007-7

Ejemplares similares