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BEDwARS: a robust Bayesian approach to bulk gene expression deconvolution with noisy reference signatures

Differential gene expression in bulk transcriptomics data can reflect change of transcript abundance within a cell type and/or change in the proportions of cell types. Expression deconvolution methods can help differentiate these scenarios. BEDwARS is a Bayesian deconvolution method designed to addr...

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Detalles Bibliográficos
Autores principales:	Ghaffari, Saba, Bouchonville, Kelly J., Saleh, Ehsan, Schmidt, Remington E., Offer, Steven M., Sinha, Saurabh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399072/ https://www.ncbi.nlm.nih.gov/pubmed/37537644 http://dx.doi.org/10.1186/s13059-023-03007-7

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