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Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors

[Image: see text] As blood cholesterol increases, it accumulates in the intima of blood vessels, elevating the risk of atherosclerosis and coronary artery disease. Drugs that inhibit enzymes essential for cholesterol synthesis are effective in improving blood cholesterol levels. Statins are used to...

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Detalles Bibliográficos
Autores principales: Samizo, Shigeyoshi, Kaneko, Hiromasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399166/
https://www.ncbi.nlm.nih.gov/pubmed/37546661
http://dx.doi.org/10.1021/acsomega.3c02567