Cargando…

Application of Allometric Scaling to Nanochelator Pharmacokinetics

[Image: see text] Deferoxamine (DFO) is an effective FDA-approved iron chelator; however, its use is considerably limited by off-target toxicities and an extremely cumbersome dose regimen involving daily infusions. The recent development of a deferoxamine-based nanochelator (DFO-NP) with selective r...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Gregory, Zeng, Lingxue, Kim, Jonghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399172/
https://www.ncbi.nlm.nih.gov/pubmed/37546686
http://dx.doi.org/10.1021/acsomega.3c02570