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Application of Allometric Scaling to Nanochelator Pharmacokinetics
[Image: see text] Deferoxamine (DFO) is an effective FDA-approved iron chelator; however, its use is considerably limited by off-target toxicities and an extremely cumbersome dose regimen involving daily infusions. The recent development of a deferoxamine-based nanochelator (DFO-NP) with selective r...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399172/ https://www.ncbi.nlm.nih.gov/pubmed/37546686 http://dx.doi.org/10.1021/acsomega.3c02570 |