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G9a inactivation in progenitor cells with Isl1-Cre with reduced recombinase activity models aspects of Dandy-Walker complex

G9a, also known as EHMT2, is essential for embryogenesis and has specific functions in multiple developmental processes. G9a inactivation affects development of the nervous system, which is formed with contribution of descendants of progenitor cells expressing the transcription factor Isl1. However,...

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Detalles Bibliográficos
Autores principales: Chi, Lijun, Zhong, Ling, Lee, Dorothy, Yu, Xinwen, Caballero, Amalia, Nieman, Brian, Delgado-Olguin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399207/
https://www.ncbi.nlm.nih.gov/pubmed/37470706
http://dx.doi.org/10.1242/bio.059894