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PTEN in triple-negative breast carcinoma: protein expression and genomic alteration in pretreatment and posttreatment specimens

BACKGROUND: Recent advances have been made in targeting the phosphoinositide 3-kinase pathway in breast cancer. Phosphatase and tensin homolog (PTEN) is a key component of that pathway. OBJECTIVE: To understand the changes in PTEN expression over the course of the disease in patients with triple-neg...

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Detalles Bibliográficos
Autores principales: Chen, Hui, Ding, Qingqing, Khazai, Laila, Zhao, Li, Damodaran, Senthil, Litton, Jennifer K., Rauch, Gaiane M., Yam, Clinton, Chang, Jeffrey T., Seth, Sahil, Lim, Bora, Thompson, Alastair M., Mittendorf, Elizabeth A., Adrada, Beatriz, Virani, Kiran, White, Jason B., Ravenberg, Elizabeth, Song, Xingzhi, Candelaria, Rosalind, Arun, Banu, Ueno, Naoto T., Santiago, Lumarie, Saleem, Sadia, Abouharb, Sausan, Murthy, Rashmi K., Ibrahim, Nuhad, Routbort, Mark J., Sahin, Aysegul, Valero, Vicente, Symmans, William Fraser, Tripathy, Debu, Wang, Wei-Lien, Moulder, Stacy, Huo, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399250/
https://www.ncbi.nlm.nih.gov/pubmed/37547448
http://dx.doi.org/10.1177/17588359231189422