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Adenosine receptor A2b confers ovarian cancer survival and PARP inhibitor resistance through IL‐6‐STAT3 signalling

Ovarian cancer is the deadliest gynecologic cancer worldwide, and the therapeutic options are limited. PARP inhibitor (PARPi) represents an effective therapeutic strategy and has been approved for maintenance therapy. However, the intrinsic or acquired resistance to PARPi becomes a big challenge. To...

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Detalles Bibliográficos
Autores principales: Chi, Liqing, Huan, Lin, Zhang, Chunyan, Wang, Hanming, Lu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399543/
https://www.ncbi.nlm.nih.gov/pubmed/37278400
http://dx.doi.org/10.1111/jcmm.17802