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GWAS reveals genetic basis of a predisposition to severe COVID-19 through in silico modeling of the FYCO1 protein

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is heavily reliant on its natural ability to “hack” the host’s genetic and biological pathways. The genetic susceptibility of the host is a key factor underlying the severity of the disease. Polygenic risk...

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Detalles Bibliográficos
Autores principales: Gusakova, Mariya S., Ivanov, Mikhail V., Kashtanova, Daria A., Taraskina, Anastasiia N., Erema, Veronika V., Mikova, Valeriya M., Loshkarev, Robert I., Ignatyeva, Olga A., Akinshina, Aleksandra I., Mitrofanov, Sergey I., Snigir, Ekaterina A., Yudin, Vladimir S., Makarov, Valentin V., Keskinov, Anton A., Yudin, Sergey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399629/
https://www.ncbi.nlm.nih.gov/pubmed/37547597
http://dx.doi.org/10.3389/fmed.2023.1178939