Cargando…

Analysis of genomic and immune intratumor heterogeneity in linitis plastica via multiregional exome and T‐cell receptor sequencing

The molecular landscape and the intratumor heterogeneity (ITH) architecture of gastric linitis plastica (LP) are poorly understood. We performed whole‐exome sequencing (WES) and T‐cell receptor (TCR) sequencing on 40 tumor regions from four LP patients. The landscape and ITH at the genomic and immun...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jin, Zhao, Guofeng, Peng, Qiu, Yi, Xin, Ji, Liyan, Li, Jing, Li, Pansong, Guan, Yanfang, Ge, Jie, Chen, Ling, Chen, Runzhe, Hu, Xin, Lee, Won‐Chul, Reuben, Alexandre, Futreal, P. Andrew, Xia, Xuefeng, Ma, Jian, Zhang, Jianjun, Chen, Zihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399711/
https://www.ncbi.nlm.nih.gov/pubmed/36703611
http://dx.doi.org/10.1002/1878-0261.13381