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Pancreatic cancer‐derived small extracellular vesical ezrin activates fibroblasts to exacerbate cancer metastasis through STAT3 and YAP‐1 signaling pathways

Cancer‐associated fibroblasts (CAFs), a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC), play an important role in tumorigenesis, metastasis, and chemoresistance. Tumor‐derived small extracellular vesicles (sEVs), which mediate cell‐to‐cell communicatio...

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Detalles Bibliográficos
Autores principales: Chang, Yu‐Ting, Peng, Hsuan‐Yu, Hu, Chun‐Mei, Tien, Sui‐Chih, Chen, Yi‐Ing, Jeng, Yung‐Ming, Chang, Ming‐Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399719/
https://www.ncbi.nlm.nih.gov/pubmed/37171030
http://dx.doi.org/10.1002/1878-0261.13442