Dual VEGFA/BRAF targeting boosts PD‐1 blockade in melanoma through GM‐CSF‐mediated infiltration of M1 macrophages

The introduction of targeted therapies represented one of the most significant advances in the treatment of BRAFV600E melanoma. However, the onset of acquired resistance remains a challenge. Previously, we showed in mouse xenografts that vascular endothelial growth factor (VEGFA) removal enhanced th...

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Detalles Bibliográficos
Autores principales: Comunanza, Valentina, Gigliotti, Chiara, Lamba, Simona, Doronzo, Gabriella, Vallariello, Edoardo, Martin, Valentina, Isella, Claudio, Medico, Enzo, Bardelli, Alberto, Sangiolo, Dario, Di Nicolantonio, Federica, Bussolino, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399721/
https://www.ncbi.nlm.nih.gov/pubmed/37183363
http://dx.doi.org/10.1002/1878-0261.13450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399721/
https://www.ncbi.nlm.nih.gov/pubmed/37183363
http://dx.doi.org/10.1002/1878-0261.13450

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