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Proliferating cell nuclear antigen inhibitors block distinct stages of herpes simplex virus infection
Proliferating cell nuclear antigen (PCNA) forms a homotrimer that encircles replicating DNA and is bound by DNA polymerases to add processivity to cellular DNA synthesis. In addition, PCNA acts as a scaffold to recruit DNA repair and chromatin remodeling proteins to replicating DNA via its interdoma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399828/ https://www.ncbi.nlm.nih.gov/pubmed/37486931 http://dx.doi.org/10.1371/journal.ppat.1011539 |