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Segregational drift hinders the evolution of antibiotic resistance on polyploid replicons
The emergence of antibiotic resistance under treatment depends on the availability of resistance alleles and their establishment in the population. Novel resistance alleles are encoded either in chromosomal or extrachromosomal genetic elements; both types may be present in multiple copies within the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399855/ https://www.ncbi.nlm.nih.gov/pubmed/37535631 http://dx.doi.org/10.1371/journal.pgen.1010829 |