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Segregational drift hinders the evolution of antibiotic resistance on polyploid replicons

The emergence of antibiotic resistance under treatment depends on the availability of resistance alleles and their establishment in the population. Novel resistance alleles are encoded either in chromosomal or extrachromosomal genetic elements; both types may be present in multiple copies within the...

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Detalles Bibliográficos
Autores principales: Garoña, Ana, Santer, Mario, Hülter, Nils F., Uecker, Hildegard, Dagan, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399855/
https://www.ncbi.nlm.nih.gov/pubmed/37535631
http://dx.doi.org/10.1371/journal.pgen.1010829

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