Vasoprotective effects of NOX4 are mediated via polymerase and transient receptor potential melastatin 2 cation channels in endothelial cells

BACKGROUND: NOX4 activation has been implicated to have vasoprotective and blood pressure (BP)-lowering effects. Molecular mechanisms underlying this are unclear, but NOX4-induced regulation of the redox-sensitive Ca(2+) channel TRPM2 and effects on endothelial nitric oxide synthase (eNOS)-nitric ox...

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Detalles Bibliográficos
Autores principales: Alves-Lopes, Rheure, Lacchini, Silvia, Neves, Karla B., Harvey, Adam, Montezano, Augusto C., Touyz, Rhian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399938/
https://www.ncbi.nlm.nih.gov/pubmed/37272080
http://dx.doi.org/10.1097/HJH.0000000000003478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399938/
https://www.ncbi.nlm.nih.gov/pubmed/37272080
http://dx.doi.org/10.1097/HJH.0000000000003478

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