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Vasoprotective effects of NOX4 are mediated via polymerase and transient receptor potential melastatin 2 cation channels in endothelial cells

BACKGROUND: NOX4 activation has been implicated to have vasoprotective and blood pressure (BP)-lowering effects. Molecular mechanisms underlying this are unclear, but NOX4-induced regulation of the redox-sensitive Ca(2+) channel TRPM2 and effects on endothelial nitric oxide synthase (eNOS)-nitric ox...

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Detalles Bibliográficos
Autores principales:	Alves-Lopes, Rheure, Lacchini, Silvia, Neves, Karla B., Harvey, Adam, Montezano, Augusto C., Touyz, Rhian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399938/ https://www.ncbi.nlm.nih.gov/pubmed/37272080 http://dx.doi.org/10.1097/HJH.0000000000003478

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