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Intra-amniotic sildenafil treatment improves lung blood flow and pulmonary hypertension in congenital diaphragmatic hernia rats

Pulmonary hypertension associated with congenital diaphragmatic hernia (CDH) is a critical factor in determining prognosis. We propose that intra-amniotic sildenafil administration is an effective prenatal therapy for CDH-induced pulmonary hypertension. To assess the efficacy of this treatment, we a...

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Detalles Bibliográficos
Autores principales: Yoshida, Shiho, Kreger, Alexander M., Gittes, George K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399963/
https://www.ncbi.nlm.nih.gov/pubmed/37545896
http://dx.doi.org/10.3389/fbioe.2023.1195623