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Partial male-to-female reprogramming of mouse fetal testis by Sertoli cell ablation

Temporal transcription profiles of fetal testes with Sertoli cell ablation were examined in 4-day culture using a diphtheria toxin (DT)-dependent cell knockout system in AMH-TRECK transgenic (Tg) mice. RNA analysis revealed that ovarian-specific genes, including Foxl2, were ectopically expressed in...

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Detalles Bibliográficos
Autores principales: Imaimatsu, Kenya, Hiramatsu, Ryuji, Tomita, Ayako, Itabashi, Hirotsugu, Kanai, Yoshiakira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399983/
https://www.ncbi.nlm.nih.gov/pubmed/37376880
http://dx.doi.org/10.1242/dev.201660