Cargando…

Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion

Accumulating evidence in several model organisms indicates that reduced sphingolipid biosynthesis promotes longevity, although underlying mechanisms remain unclear. In yeast, sphingolipid depletion induces a state resembling amino acid restriction, which we hypothesized might be due to altered stabi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hepowit, Nathaniel L., Moon, Bradley, Ebert, Adam C., Dickson, Robert C., MacGurn, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399987/
https://www.ncbi.nlm.nih.gov/pubmed/37337792
http://dx.doi.org/10.1242/jcs.260675