The lipid transfer proteins Nir2 and Nir3 sustain phosphoinositide signaling and actin dynamics during phagocytosis

Changes in membrane phosphoinositides and local Ca(2+) elevations at sites of particle capture coordinate the dynamic remodeling of the actin cytoskeleton during phagocytosis. Here, we show that the phosphatidylinositol (PI) transfer proteins PITPNM1 (Nir2) and PITPNM2 (Nir3) maintain phosphatidylin...

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Detalles Bibliográficos
Autores principales: Kaba, Mayis, Carreras-Sureda, Amado, Nunes-Hasler, Paula, Demaurex, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399989/
https://www.ncbi.nlm.nih.gov/pubmed/37376972
http://dx.doi.org/10.1242/jcs.260902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399989/
https://www.ncbi.nlm.nih.gov/pubmed/37376972
http://dx.doi.org/10.1242/jcs.260902

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