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Structural insight into guanylyl cyclase receptor hijacking of the kinase–Hsp90 regulatory mechanism

Membrane receptor guanylyl cyclases play a role in many important facets of human physiology, from regulating blood pressure to intestinal fluid secretion. The structural mechanisms which influence these important physiological processes have yet to be explored. We present the 3.9 Å resolution cryo-...

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Detalles Bibliográficos
Autores principales: Caveney, Nathanael A, Tsutsumi, Naotaka, Garcia, K Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400071/
https://www.ncbi.nlm.nih.gov/pubmed/37535399
http://dx.doi.org/10.7554/eLife.86784