p38γ and p38δ modulate innate immune response by regulating MEF2D activation

Evidence implicating p38γ and p38δ (p38γ/p38δ) in inflammation are mainly based on experiments using Mapk12/Mapk13-deficient (p38γ/δKO) mice, which show low levels of TPL2, the kinase upstream of MKK1–ERK1/2 in myeloid cells. This could obscure p38γ/p38δ roles, since TPL2 is essential for regulating...

Descripción completa

Detalles Bibliográficos
Autores principales: Escós, Alejandra, Diaz-Mora, Ester, Pattison, Michael, Fajardo, Pilar, González-Romero, Diego, Risco, Ana, Martín-Gómez, José, Bonneil, Éric, Sonenberg, Nahum, Jafarnejad, Seyed Mehdi, Sanz-Ezquerro, Juan José, Ley, Steven C, Cuenda, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400073/
https://www.ncbi.nlm.nih.gov/pubmed/37458356
http://dx.doi.org/10.7554/eLife.86200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400073/
https://www.ncbi.nlm.nih.gov/pubmed/37458356
http://dx.doi.org/10.7554/eLife.86200

Ejemplares similares