Structural and mechanistic insights into the MCM8/9 helicase complex

MCM8 and MCM9 form a functional helicase complex (MCM8/9) that plays an essential role in DNA homologous recombination repair for DNA double-strand break. However, the structural characterization of MCM8/9 for DNA binding/unwinding remains unclear. Here, we report structures of the MCM8/9 complex us...

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Detalles Bibliográficos
Autores principales: Weng, Zhuangfeng, Zheng, Jiefu, Zhou, Yiyi, Lu, Zuer, Wu, Yixi, Xu, Dongyi, Li, Huanhuan, Liang, Huanhuan, Liu, Yingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400076/
https://www.ncbi.nlm.nih.gov/pubmed/37535404
http://dx.doi.org/10.7554/eLife.87468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400076/
https://www.ncbi.nlm.nih.gov/pubmed/37535404
http://dx.doi.org/10.7554/eLife.87468

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