Integration of Multi-omic Data in a Molecular Tumor Board Reveals EGFR-Associated ALK-Inhibitor Resistance in a Patient With Inflammatory Myofibroblastic Cancer

Inflammatory myofibroblastic tumors (IMTs) are intermediate-grade mesenchymal neoplasms commonly characterized by chromosomal rearrangements causing constitutive activation of anaplastic lymphoma kinase (ALK) and/or ALK mutations causing reduced sensitivity to ALK tyrosine kinase inhibitors (TKI). W...

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Detalles Bibliográficos
Autores principales: Hunt, Allison L, Nutcharoen, Aratara, Randall, Jamie, Papazian, Alyssa, Deeken, John, Maxwell, G Larry, Bateman, Nicholas W, Petricoin, Emanuel F, Benyounes, Amin, Conrads, Thomas P, Cannon, Timothy L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Precision Medicine Clinic: Molecular Tumor Board
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400139/
https://www.ncbi.nlm.nih.gov/pubmed/37255276
http://dx.doi.org/10.1093/oncolo/oyad129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400139/
https://www.ncbi.nlm.nih.gov/pubmed/37255276
http://dx.doi.org/10.1093/oncolo/oyad129

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