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Integration of Multi-omic Data in a Molecular Tumor Board Reveals EGFR-Associated ALK-Inhibitor Resistance in a Patient With Inflammatory Myofibroblastic Cancer
Inflammatory myofibroblastic tumors (IMTs) are intermediate-grade mesenchymal neoplasms commonly characterized by chromosomal rearrangements causing constitutive activation of anaplastic lymphoma kinase (ALK) and/or ALK mutations causing reduced sensitivity to ALK tyrosine kinase inhibitors (TKI). W...
Autores principales: | Hunt, Allison L, Nutcharoen, Aratara, Randall, Jamie, Papazian, Alyssa, Deeken, John, Maxwell, G Larry, Bateman, Nicholas W, Petricoin, Emanuel F, Benyounes, Amin, Conrads, Thomas P, Cannon, Timothy L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400139/ https://www.ncbi.nlm.nih.gov/pubmed/37255276 http://dx.doi.org/10.1093/oncolo/oyad129 |
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