Phylogenetic Reconstruction and Functional Characterization of the Ancestral Nef Protein of Primate Lentiviruses

Nef is an accessory protein unique to the primate HIV-1, HIV-2, and SIV lentiviruses. During infection, Nef functions by interacting with multiple host proteins within infected cells to evade the immune response and enhance virion infectivity. Notably, Nef can counter immune regulators such as CD4 a...

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Detalles Bibliográficos
Autores principales: Olabode, Abayomi S, Mumby, Mitchell J, Wild, Tristan A, Muñoz-Baena, Laura, Dikeakos, Jimmy D, Poon, Art F Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400143/
https://www.ncbi.nlm.nih.gov/pubmed/37463439
http://dx.doi.org/10.1093/molbev/msad164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400143/
https://www.ncbi.nlm.nih.gov/pubmed/37463439
http://dx.doi.org/10.1093/molbev/msad164

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