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Surface plasmon resonance and microscale thermophoresis approaches for determining the affinity of perforin for calcium ions
Perforin is a pore-forming protein that plays a crucial role in the immune system by clearing virus-infected or tumor cells. It is released from cytotoxic granules of immune cells and forms pores in targeted lipid membranes to deliver apoptosis-inducing granzymes. It is a very cytotoxic protein and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400287/ https://www.ncbi.nlm.nih.gov/pubmed/37545534 http://dx.doi.org/10.3389/fimmu.2023.1181020 |