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Sustained heterologous gene expression in pancreatic islet organoids using adeno-associated virus serotype 8
Genetic modification of pancreatic islet organoids, assembled in vitro prior to transplantation is an emerging alternative to direct in vivo genetic manipulations for a number of clinical and research applications. We have previously shown that dispersion of islet cells followed by re-aggregation in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400289/ https://www.ncbi.nlm.nih.gov/pubmed/37545890 http://dx.doi.org/10.3389/fbioe.2023.1147244 |