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Sustained heterologous gene expression in pancreatic islet organoids using adeno-associated virus serotype 8

Genetic modification of pancreatic islet organoids, assembled in vitro prior to transplantation is an emerging alternative to direct in vivo genetic manipulations for a number of clinical and research applications. We have previously shown that dispersion of islet cells followed by re-aggregation in...

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Detalles Bibliográficos
Autores principales: Voznesenskaya, Anna, Berggren, Per-Olof, Ilegems, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400289/
https://www.ncbi.nlm.nih.gov/pubmed/37545890
http://dx.doi.org/10.3389/fbioe.2023.1147244

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