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ReCo: automated NGS read-counting of single and combinatorial CRISPR gRNAs

SUMMARY: CRISPR screens are increasingly performed to associate genotypes with genotypes. So far, however, their analysis required specialized computational knowledge to transform high-throughput next-generation sequencing (NGS) data into sequence formats amenable for downstream analysis. We develop...

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Detalles Bibliográficos
Autores principales: Wegner, Martin, Kaulich, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400375/
https://www.ncbi.nlm.nih.gov/pubmed/37481709
http://dx.doi.org/10.1093/bioinformatics/btad448