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ReCo: automated NGS read-counting of single and combinatorial CRISPR gRNAs
SUMMARY: CRISPR screens are increasingly performed to associate genotypes with genotypes. So far, however, their analysis required specialized computational knowledge to transform high-throughput next-generation sequencing (NGS) data into sequence formats amenable for downstream analysis. We develop...
Autores principales: | Wegner, Martin, Kaulich, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400375/ https://www.ncbi.nlm.nih.gov/pubmed/37481709 http://dx.doi.org/10.1093/bioinformatics/btad448 |
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