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Should a matched sibling donor still be considered the primary option for allogeneic hematopoietic cell transplantation in patients over 50 years of age with myelodysplastic syndrome?

Human leukocyte antigen (HLA)-matched sibling donors (MSDs) are the preferred choice for allogeneic hematopoietic cell transplantation (HCT). However, as myelodysplastic syndrome (MDS) is most frequently diagnosed in the elderly, MSDs are also likely to be of advanced age. It is unclear whether an M...

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Detalles Bibliográficos
Autores principales: Konuma, Takaaki, Itonaga, Hidehiro, Ishiyama, Ken, Doki, Noriko, Uchida, Naoyuki, Sawa, Masashi, Katayama, Yuta, Tanaka, Masatsugu, Ueda, Yasunori, Onizuka, Makoto, Miyakoshi, Shigesaburo, Ozawa, Yukiyasu, Fukuda, Takahiro, Matsuoka, Ken-ichi, Tanaka, Junji, Kimura, Takafumi, Ichinohe, Tatsuo, Atsuta, Yoshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400426/
https://www.ncbi.nlm.nih.gov/pubmed/37156881
http://dx.doi.org/10.1038/s41409-023-01997-3