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The DOTA macrocyclic cavity in metallic radiopharmaceuticals: Mythology or reality?
BACKGROUND: The hypothetical concept of ‘macrocyclic cavity’ is largely employed as useful model to interpret the affinity of metal ions for the macrocyclic chelating ligand 2,2′,2′′,2′′′-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (H(4)DOTA). It Is hypothesized that a close ma...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer International Publishing
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400501/ https://www.ncbi.nlm.nih.gov/pubmed/37535275 http://dx.doi.org/10.1186/s41181-023-00202-6 |