Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis

Using multiple mouse models, we explored the impact of aging on the size and severity of atherosclerotic lesions. In young, middle-aged and old apolipoprotein E knockout mice (ApoE(−/−)) fed an atherogenic diet (AD) for 3–8 weeks, plaque/atheroma formation in the descending aorta and aortic root, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Gogulamudi, Venkateswara R., Durrant, Jessica R., Adeyemo, Adelola O., Ho, Huynh Mi, Walker, Ashley E., Lesniewski, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400524/
https://www.ncbi.nlm.nih.gov/pubmed/37086367
http://dx.doi.org/10.1007/s11357-023-00776-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400524/
https://www.ncbi.nlm.nih.gov/pubmed/37086367
http://dx.doi.org/10.1007/s11357-023-00776-8

Ejemplares similares