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Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis
Using multiple mouse models, we explored the impact of aging on the size and severity of atherosclerotic lesions. In young, middle-aged and old apolipoprotein E knockout mice (ApoE(−/−)) fed an atherogenic diet (AD) for 3–8 weeks, plaque/atheroma formation in the descending aorta and aortic root, an...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400524/ https://www.ncbi.nlm.nih.gov/pubmed/37086367 http://dx.doi.org/10.1007/s11357-023-00776-8 |